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KMID : 0357920010350060551
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Korean Journal of Pathology
2001 Volume.35 No. 6 p.551 ~ p.554
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Mesoblastic Nephroma of Adulthood -A Case Report-
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Park Jae-Woo
Chung Jae-Hun
Lee Jae-Hyuk
Nam Jong-Hee
Choi Chan
Lee Min-Cheol
Park Chang-Soo
Juhng Sang-Woo
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Abstract
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Mesoblastic nephroma is a benign neoplasm of the kidney, which is usually diagnosed during the first six months of life. Incidence in adults is exceedingly rare. We report herein a case of mesoblastic nephroma that occurred in the upper pole of the right kidney of a 39-year-old woman. It was a round mass measuring 3×3×2 ㎝ in dimension. Microscopically, it consisted of uniform spindle cells with foci of hyalinization and dystrophic calcification. Tubular structures were entrapped in the tumor. Upon immunohistochemical staining, the spindle cells were found to be positive for smooth muscle actin, desmin, and vimentin. The epithelial cells of the entrapped tubules were positive for cytokeratin. On electron microscopic examination, the spindle cells demonstrated smooth muscle differentiation identified by indented nuclei, microfilaments beneath the cell membrane, dense bodies, and basal lamina-like materials.
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KEYWORD
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Nephroma, mesoblastic
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